MyMyelomaTeam

What does CRAB mean in multiple myeloma?

CRAB is an acronym that describes the main ways myeloma can cause organ damage and harm to your body. These symptoms signal that someone has active multiple myeloma rather than an earlier condition like MGUS or smoldering myeloma.

Here's what CRAB stands for:

- C - Calcium levels Show Full Answer

What does CRAB mean in multiple myeloma?

CRAB is an acronym that describes the main ways myeloma can cause organ damage and harm to your body. These symptoms signal that someone has active multiple myeloma rather than an earlier condition like MGUS or smoldering myeloma.

Here's what CRAB stands for:

- C - Calcium levels that are high (hypercalcemia)
- R - Renal (kidney) damage or failure
- A - Anemia (low red blood cell count)
- B - Bone lesions (damage, tumors, or soft spots in bones)

The bone lesions happen because myeloma cells grow in your bone marrow and weaken the hard bone around it. This creates soft spots that can lead to fractures and pain.

If you develop CRAB symptoms, it means the myeloma needs treatment to prevent further damage. Your healthcare team will work with you to address both the symptoms and the underlying disease.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

Multiple Myeloma: Bone Lesions, Damage, and Pain

Understanding Hypercalcemia and Multiple Myeloma