What are the chances of losing teeth due to multiple myeloma and treatment while taking Revlimid?
The good news is that Revlimid (lenalidomide) itself isn't typically associated with direct dental problems or tooth loss. However, myeloma and certain other treatments can affect your oral health.
Here are the main dental Show Full Answer
What are the chances of losing teeth due to multiple myeloma and treatment while taking Revlimid?
The good news is that Revlimid (lenalidomide) itself isn't typically associated with direct dental problems or tooth loss. However, myeloma and certain other treatments can affect your oral health.
Here are the main dental concerns with myeloma:
Bone-related issues:
- 30-35% of people with myeloma experience disease spread to the jaw, which can cause loose teeth, jaw pain, and swelling
- 70-80% develop bone disease overall, though the jaw isn't among the most commonly affected areas
Treatment-related risks:
If you're taking bisphosphonates (like Zometa) or denosumab (Xgeva) alongside Revlimid, there's a higher risk of osteonecrosis of the jaw (ONJ). This affects 3-11% of people taking these medications, with risk increasing over time. ONJ can lead to loose teeth and exposed jawbone.
Other concerns:
- Gum tumors occur in 8-15% of people with myeloma
- Chemotherapy can cause gum bleeding, mouth pain, and infections Protecting your teeth:
Regular dental checkups and good oral hygiene are essential. Make sure both your oncologist and dentist communicate about your care. If you need invasive dental work and you're on bisphosphonates, treatment should be paused 90 days before and after the procedure.
A MyMyelomaTeam member advised: "Make sure you get regular dental visits. I developed osteonecrosis, and it was diagnosed on a routine dental exam."
Early detection and preventive care can significantly reduce your risk of serious dental problems.
April 4