Why do some myeloma patients experience intense, constant pain?
Myeloma causes intense, constant pain primarily because abnormal plasma cells build up in the bones, creating tumors and bone lesions that destroy bone faster than it can rebuild. This bone damage is a major source of ongoing pain.
Here are the main reasons Show Full Answer
Why do some myeloma patients experience intense, constant pain?
Myeloma causes intense, constant pain primarily because abnormal plasma cells build up in the bones, creating tumors and bone lesions that destroy bone faster than it can rebuild. This bone damage is a major source of ongoing pain.
Here are the main reasons for persistent pain:
- Bone lesions: These areas of bone destruction weaken bones and cause deep, dull, or excruciating pain that many describe as unrelenting
- Fractures: Weakened bones break more easily, and these fractures take longer to heal in myeloma patients, leading to prolonged pain
- Spinal compression: Vertebral fractures can compress the spinal cord, causing severe nerve pain that radiates to other areas like the legs
- Nerve damage: Myeloma cells can damage nerves directly, causing peripheral neuropathy with burning, tingling, or constant pain in the extremities
The pain can be so severe that it interferes with sleep, daily activities, and quality of life. As one MyMyelomaTeam member shared, "Nothing can seem to kill the pain, so I get maybe one or two hours of sleep a night."
If you're experiencing intense, constant pain, it's crucial to talk with your doctor about pain management options, which may include medications, radiation therapy, or bone-strengthening treatments.
March 7