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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I have problems with lenalidomide side effects. I want to hear how others are managing with lenalidomide.

A MyMyelomaTeam Member asked a question 💭
January 22
 · 
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A MyMyelomaTeam Member

I was on Lenalidomide and couldn’t tolerate it. Three attempts all brought me out in a full body rash. I was like a lobster and so very uncomfortable and itchy. Now on injections.

January 23
A MyMyelomaTeam Member

My first two doses I had a rash took allergy meds to help. Other than that I don't believe any side effects but I do like the seven days off! Please let your Dr/team know so they can help you. I keep a simple daily journal on my phone for meds/side effects and questions for my next visit.

January 23 (edited)
MyMyelomaTeam

How are others managing lenalidomide side effects?

Lenalidomide is generally well tolerated, but at least 20 percent of people taking it experience side effects. The most common ones include:

- Diarrhea or constipation
- Fatigue
- Swelling in arms or legs
- Insomnia
- Muscle cramps or spasms
- Abdominal or back pain
- Show Full Answer

How are others managing lenalidomide side effects?

Lenalidomide is generally well tolerated, but at least 20 percent of people taking it experience side effects. The most common ones include:

- Diarrhea or constipation
- Fatigue
- Swelling in arms or legs
- Insomnia
- Muscle cramps or spasms
- Abdominal or back pain
- Nausea
- Fever
- Respiratory and digestive tract infections
- Cough and shortness of breath
- Rash
- Dizziness and loss of appetite

The key is reporting any side effects to your doctor. They can often help you find ways to manage uncomfortable symptoms and improve your quality of life.

Some people experience rashes with lenalidomide. Studies show that outcomes can vary, but your healthcare team can work with you to address skin reactions if they occur.

If side effects become too challenging, don't hesitate to reach out to your healthcare team. They may be able to adjust your dose or suggest supportive treatments to help you stay on track with your maintenance therapy.

January 22

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