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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyMyelomaTeam Member asked a question 💭
Lee, MA

One thing I wasn't prepared for while on treatment was brain fog. It got to a point where I occasionally couldn’t remember something that happened in the morning by that afternoon. Things like…did I really put the trash bins out for garbage pickup? Concerned, I brought these lapses in my mental state up to my oncologist at Dana-Farber. She laughed and told me brain fog was indeed a recognized and well-documented side effect of MM cancer treatment and of the disease itself. What?!? This was… read more

January 12
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A MyMyelomaTeam Member

Sharing this with MM Team 🙏

Brain Fog and Multiple Myeloma – Summary for Sharing
What it is: Brain fog is a common experience in multiple myeloma, causing difficulty with focus, memory, word-finding, and mental clarity.
Why it happens: Contributing factors include treatments (chemotherapy, steroids, immunotherapy), fatigue, anemia, sleep problems, stress, pain, medications, and infections.
Impact: It can affect daily tasks, confidence, and emotional well-being, but it does not reflect intelligence or motivation.
Management strategies:
Track symptoms and triggers
Take mental breaks and pace activities
Use written reminders or notes
Prioritize sleep, hydration, and nutrition
Light physical and mental exercises
Communicate with healthcare teams about cognitive changes
Outlook: Brain fog is often temporary or manageable. With proper care and support, most people see improvement over time.

Key message:
Brain fog is real and valid. Awareness, practical coping strategies, and support can make it easier to manage while living with multiple myeloma.

January 23
A MyMyelomaTeam Member

I'm a Relapsed/Refractory patient, so little hope for me! (Just joking!) But, as a 95-year-old 12-year survivor who just published his memoir, "Love Lifted Me," I don't have much to complain about. And this is my prayer for us all: “May the Lord guide us with His wisdom, steady our steps, and keep our hearts turned toward Him. As we walk in His ways, may He bring healing to our bodies and refreshment to our bones, filling our days with strength, peace, and renewed hope." Proverbs 3:7-8 (alt.) Amen!

January 12
A MyMyelomaTeam Member

chemo brain is what I thought it was, till I found out " Revlimid" is not chemo.....
Also the term " chemo" , basically means chemical treatment, in general......for MM or any cancer. After over 4 yrs. I still have brain fog ( slower thinking, communicating with missed or forgotten verbiage, and even slower movements). I'm just guessing, but I think the treatments accelerate us into senior symptoms ...earlier. I remember, from working as a caregiving that the " fog " was common with age. MM/treatment just shoves us into " Old" faster. Even my dexterity is off and balance, and lack of certain....emotions ( ?), like losing interest in things I used to enjoy or automatically doing things that needed to be done without hesitation. All of this in just the few years since diagnosis. Actually it's not easy to explain clearly......but I hope you get the jist. I know someone who has been off of all treatment for almost 30 yrs and he still has "chemo brain". I have to say though, that he went through a lot more treatments than me. I only had "standard treatment" and that was enough for this "side effect". He is an MM coach now and I have followed him since my diagnosis in 2018. This reminds me to send him an email, because I've noticed he has really slowed down with his member posts. YES, brain fag/chemo brain, is real. Age kind of complicates it into an excuse.

January 12 (edited)
MyMyelomaTeam

Is brain fog really a thing with multiple myeloma?

Absolutely, yes. Brain fog is a recognized symptom that can come from both myeloma itself and its treatments. You're definitely not imagining it, and your oncologist was right to validate your experience.

Many people with myeloma experience cognitive changes that include:

Show Full Answer

Is brain fog really a thing with multiple myeloma?

Absolutely, yes. Brain fog is a recognized symptom that can come from both myeloma itself and its treatments. You're definitely not imagining it, and your oncologist was right to validate your experience.

Many people with myeloma experience cognitive changes that include:

* Difficulty paying attention and concentrating
* Memory problems with short-term information
* Trouble multitasking
* Slower thinking and processing
* Difficulty following instructions or conversations
* Feeling like thoughts are unclear or "foggy"

The longer someone lives with myeloma, the more likely they are to notice these changes. Researchers aren't entirely sure whether cognitive decline comes from the cancer itself, the treatments, or a combination of factors. What causes brain fog in myeloma?

Several factors can contribute:

* High calcium levels in the blood (hypercalcemia) can affect brain function
* Abnormal proteins from myeloma cells can interfere with blood flow in the brain
* Anemia (low red blood cell count) reduces oxygen delivery to the brain
* Treatment side effects, often called "chemo brain"
* Fatigue and poor sleep quality can worsen cognitive symptoms

A MyMyelomaTeam member shared similar experiences with treatment side effects. The good news is that many people find their cognitive function improves after treatment ends, though recovery time varies from person to person.

If you notice new or worsening cognitive symptoms, talk to your doctor. They can help identify contributing factors and suggest strategies to manage these effects.

January 12
A MyMyelomaTeam Member

To me, it is no.

January 12

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A MyMyelomaTeam Member asked a question 💭

A MyMyelomaTeam Member asked a question 💭
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