What are the specific signs of relapse in multiple myeloma and what blood test markers do doctors monitor to detect relapse?
Relapse in multiple myeloma can show up through various symptoms and test results. Here are the key signs to watch for:
Common Physical Symptoms
- Frequent infections due to low white blood cell Show Full Answer
What are the specific signs of relapse in multiple myeloma and what blood test markers do doctors monitor to detect relapse?
Relapse in multiple myeloma can show up through various symptoms and test results. Here are the key signs to watch for:
Common Physical Symptoms:
- Frequent infections due to low white blood cell counts
- Easy bruising or bleeding from low platelet levels
- Bone pain, especially in your back, hips, or skull
- Weakness and fatigue from anemia
- Neurological issues like dizziness, blurred vision, or numbness
- Kidney problems causing swelling in legs or hands
Blood Test Markers Doctors Monitor:
Your doctor will track several important markers:
- M protein levels (measured through protein electrophoresis)
- Serum-free light chains ratios
- Calcium levels (hypercalcemia is a warning sign)
- Hemoglobin levels to check for anemia
- Creatinine levels to assess kidney function
- Beta-2 microglobulin levels
- Plasma cell percentage in bone marrow
Doctors often use the CRAB criteria to diagnose relapse, which includes Calcium elevation, Renal impairment, Anemia, and Bone disease.
Even minor symptoms shouldn't be ignored. If you notice new or worsening symptoms, reach out to your healthcare team right away. They can run tests to determine if it's a relapse and discuss treatment options if needed.
January 10
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