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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyMyelomaTeam Member asked a question 💭
Santa Monica, CA
December 26, 2025
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A MyMyelomaTeam Member

Yes, it took me a while to figure out why my white count was always low on my blood work. Darn Revlimid was lowering it. I noticed when I went to 5 mg Revlimid all my numbers looked better. It’s amazing they can figure this out! Happy New Year!

December 26, 2025
A MyMyelomaTeam Member

It's a side effect. My dosage had to be adjusted due to low counts a few times.

December 26, 2025
A MyMyelomaTeam Member

According to my Doctora YES it is normal for the while count to drop while on Revlimid . Mine hangs around 2.3-2.9 Rev is 26 mg,/21/7

December 28, 2025
A MyMyelomaTeam Member

I was not able to take Revlimid. I’m sorry I’m not able to comment.

December 26, 2025
MyMyelomaTeam

Is it normal to have a low white blood cell count while on Revlimid?

Yes, changes in blood counts, including low white blood cells, are a known side effect of lenalidomide (Revlimid). This is something your doctor will monitor during your follow-up visits.

Revlimid is an immunomodulatory drug commonly used in myeloma Show Full Answer

Is it normal to have a low white blood cell count while on Revlimid?

Yes, changes in blood counts, including low white blood cells, are a known side effect of lenalidomide (Revlimid). This is something your doctor will monitor during your follow-up visits.

Revlimid is an immunomodulatory drug commonly used in myeloma treatment, particularly for maintenance therapy. While it's generally well-tolerated, it can increase the risk of blood count changes.

When white blood cells are low, your immune system can't protect your body as effectively, which puts you at higher risk for infections. If you're getting sick often or staying sick longer than usual, it's important to let your healthcare team know.

Your doctor will regularly check your blood counts through blood tests to ensure they stay within a safe range. If your white blood cell count drops too low, they may adjust your dosage or recommend other interventions to help manage this side effect.

Always report any signs of infection to your doctor, such as fever, persistent cough, new rashes, or other unusual symptoms.

December 26, 2025

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