Hi Tammy,
I have an area on my right humerus (upper arm) that they call a bone island, but they really don’t know what it is. With every MRI, PET or CT scan, they check to see if it has changed in size and so far it has not changed.
Paula🌹
December 11, 2025
Should you be worried if a sclerotic lesion was found on a PET scan?
Finding a sclerotic lesion on a PET scan warrants attention, but it's important not to panic. Sclerotic lesions are areas of bone that appear denser or harder than normal bone tissue.
In the context of myeloma, sclerotic lesions are actually less common Show Full Answer
Should you be worried if a sclerotic lesion was found on a PET scan?
Finding a sclerotic lesion on a PET scan warrants attention, but it's important not to panic. Sclerotic lesions are areas of bone that appear denser or harder than normal bone tissue.
In the context of myeloma, sclerotic lesions are actually less common than the typical lytic (bone-weakening) lesions. They're associated with a rare variant called osteosclerotic myeloma, which represents only about 3% of all myeloma cases.
Here's what you should know:
What this finding means:
- Sclerotic lesions show up as areas of increased bone density
- They can be detected through imaging like PET scans and X-rays
- Finding even one lesion requires further evaluation
Next steps:
- Your doctor will likely order additional tests to understand what's causing the lesion
- This may include blood tests, bone marrow biopsy, and other imaging studies
- They'll check for abnormal proteins and plasma cell counts
The most important thing is to discuss these results with your healthcare team. They can interpret the findings in the context of your complete medical picture and determine whether this indicates myeloma progression or another issue entirely.
December 9, 2025
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