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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
October 31, 2025
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Has myeloma or its treatments caused severe dental problems requiring all your teeth to be removed?

Yes, some MyMyelomaTeam members have experienced serious dental issues requiring multiple tooth extractions. Myeloma can affect oral health in several ways that might lead to tooth loss:

Direct effects of myeloma
* Bone Show Full Answer

Has myeloma or its treatments caused severe dental problems requiring all your teeth to be removed?

Yes, some MyMyelomaTeam members have experienced serious dental issues requiring multiple tooth extractions. Myeloma can affect oral health in several ways that might lead to tooth loss:

Direct effects of myeloma:
* Bone disease affects 70-80% of people with myeloma, and while the jaw isn't the most common site, it can be affected
* Myeloma spreads to the jaw in 30-35% of cases, causing loose teeth, jaw pain, and other problems
* Gingival tumors (gum masses) occur in 8-15% of people with myeloma

Treatment-related issues:
* Bisphosphonates and denosumab (used to treat bone damage) can cause osteonecrosis of the jaw (ONJ), affecting 3-11% of people taking these medications
* Chemotherapy can cause bleeding gums, mouth pain, infections, and other oral problems that make teeth harder to maintain

One member shared: "After my first week of chemo, my gums have started bleeding." Another reported: "My gums and teeth hurt to the extent that it is hard to eat." Important considerations for tooth removal:

If you're taking bisphosphonates or denosumab, these medications should ideally be paused for 90 days before and after dental surgery to reduce ONJ risk. Make sure your oncologist and dentist communicate about your care plan.

Having preventive dental care and catching issues early through regular checkups can help, though it sounds like you're already facing advanced problems. Your care team can help manage the removal process safely given your myeloma treatments.

October 31, 2025

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