Bone lesions are not MGUS. It sounds like you need a full myeloma workup
September 20, 2025 (edited)
I agree, you need a full workup, God bless you!
September 20, 2025
@A MyMyelomaTeam Member It sounds like you are progressing beyond MGUS. I’m glad your doctor is ordering a PET scan, that will help them know where the MM is active. I hope you get some answers and I hope you are feeling better soon
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A MyMyelo...
September 18, 2025
While MGUS typically doesn't cause symptoms or bone lesions, the presence of skull lesions may indicate progression beyond MGUS. This finding warrants further investigation, as bone lesions are more commonly associated with multiple myeloma rather than MGUS.
It's understandable that this is concerning, especially since you Show Full Answer
While MGUS typically doesn't cause symptoms or bone lesions, the presence of skull lesions may indicate progression beyond MGUS. This finding warrants further investigation, as bone lesions are more commonly associated with multiple myeloma rather than MGUS.
It's understandable that this is concerning, especially since you were told MGUS has no symptoms. You're right - MGUS itself typically doesn't cause symptoms or bone problems. Your healthcare team is taking the right steps by ordering additional imaging (PET scan). These tests, along with blood work and possibly a bone marrow biopsy, help determine if there has been any progression from MGUS. Regular monitoring is essential as MGUS can progress to multiple myeloma in some cases, though this happens in only about 1% of people per year.
Make sure to discuss these findings with your hematologist, who can explain what the lesions mean in your specific case and determine the best course of action.
September 18, 2025