Immunoglobulin G (IgG) or IgM, IgA, IgE, or IgD are your body’s antibodies and its defense against infections. They’re an important part of your system immune system. When their numbers go up, you’re fighting an infection. The molecule is made up of two heavy chains and two light chains (either kappa or lambda). The light chains have binding sites attached to them to attack a source of an infection, like a virus or bacteria. Unfortunately with MM, the body produces an over abundance of these light chains that causes major health problems. Donna has IgG Lambda MM. I’m IgG Kappa MM. If you have had your blood work done recently, check your immunoglobulin and light chain results.
IgG monoclonal protein in bone marrow indicates the presence of multiple myeloma, where plasma cells have become cancerous. IgG is the most common type of myeloma, affecting almost half of all people with the condition. In this case, the cancerous plasma cells are producing large quantities of abnormal IgG antibodies (also Show Full Answer
It means you could have IgG myeloma. Or MGUS or smoldering myeloma. IgG is the most common type. IgG is your 'heavy chain'. You will want to know which light chain you have. Either kappa or lambda. I am IgG lambda myeloma for example.
I have light ch I was in stage 3cbone marr was 80