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A MyMyelomaTeam Member asked a question 💭
Corte Madera, CA
August 21, 2025
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MyMyelomaTeam

IgG lambda monoclonal protein indicates the presence of abnormal antibodies (also called M protein) produced by myeloma cells. IgG is the most common type of myeloma, occurring in about half of all cases. These abnormal proteins cannot fight infection properly and may cause damage to your kidneys and bones.

The presence of Show Full Answer

IgG lambda monoclonal protein indicates the presence of abnormal antibodies (also called M protein) produced by myeloma cells. IgG is the most common type of myeloma, occurring in about half of all cases. These abnormal proteins cannot fight infection properly and may cause damage to your kidneys and bones.

The presence of IgG type myeloma generally indicates a better prognosis compared to some other types, like IgA myeloma. Doctors use various tests to measure these proteins and monitor your condition:
• Immunofixation electrophoresis (IFE) to identify the specific type of protein
• Quantitative immunoglobulins test to measure protein levels
• Serum protein electrophoresis (SPEP) to track disease progression

These tests help your healthcare team determine treatment effectiveness and monitor for potential relapse.

August 21, 2025
A MyMyelomaTeam Member

It means you have some cancerous plasma cells producing clones of themselves. IgG Kappa is the most common type. You are like me. I have IgG lambda. You will want to consult with a myeloma specialist to see if you are MGUS or smoldering or active myeloma that needs treatment. I'm sorry you are dealing with this, but thankfully, it is extremely treatable.

August 23, 2025
A MyMyelomaTeam Member

M proto us kidney damage

August 22, 2025

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