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July 21, 2025
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Question: What are the chances of getting a clean biopsy result when Serum Free Light Chain (SFLC) Lambda values are high in multiple myeloma?

High SFLC scores often indicate a poorer prognosis in multiple myeloma. The bone marrow biopsy is essential for determining the number of abnormal plasma cells present and checking Show Full Answer

Question: What are the chances of getting a clean biopsy result when Serum Free Light Chain (SFLC) Lambda values are high in multiple myeloma?

High SFLC scores often indicate a poorer prognosis in multiple myeloma. The bone marrow biopsy is essential for determining the number of abnormal plasma cells present and checking for specific genetic changes in cancer cells. The biopsy results will be analyzed through cytogenetic studies to check for specific chromosome changes that could indicate more aggressive disease. Three specific chromosome changes are considered "high risk" while others are "standard risk." These findings, along with other factors like albumin levels and beta-2 microglobulin levels, help determine the stage and prognosis of the disease.

July 21, 2025

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