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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
July 18, 2025
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A MyMyelomaTeam Member

I wear compression socks during the day to help keep the swelling down to prevent blood clotting

July 18, 2025
A MyMyelomaTeam Member

Your doctor needs to evaluate the swelling. It has lots of causes. Could just be venous insufficiency or something more.

July 18, 2025
A MyMyelomaTeam Member

Hey Wendell 👋

July 21, 2025
MyMyelomaTeam

Leg swelling and pain in myeloma can occur for several reasons. Multiple myeloma can affect your body in ways that lead to swelling, particularly when standing for long periods. This is often related to:

- Nerve damage (peripheral neuropathy) affecting the legs
- Blood protein changes that impact circulation
- Kidney Show Full Answer

Leg swelling and pain in myeloma can occur for several reasons. Multiple myeloma can affect your body in ways that lead to swelling, particularly when standing for long periods. This is often related to:

- Nerve damage (peripheral neuropathy) affecting the legs
- Blood protein changes that impact circulation
- Kidney function changes that can cause fluid retention It's important to discuss this symptom with your healthcare provider, as they may want to run blood tests to determine the exact cause and best treatment approach. In the meantime, try to:

- Take regular breaks from standing
- Elevate your legs when possible
- Use compression stockings if approved by your doctor
- Keep track of when swelling occurs and what makes it better or worse

July 18, 2025

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