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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

My FLC ratio is 2.2 and only on single Bortizomib without any steroid.

June 16, 2025
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A MyMyelomaTeam Member

Call your oncologist right away about your kidney labs. This is very important.

June 16, 2025
A MyMyelomaTeam Member

Hi Abhinay, you will need to discuss your kidney function with your doctor. My specialist still has me doing a 24 hour urine test every 6 months as well as a full myeloma panel from my blood. Some patients can still have higher light chains in their urine.

June 16, 2025 (edited)
A MyMyelomaTeam Member

My dr said I should drink 96oz of water daily. I have Kappa Light Chain with 1q gain which makes me venerable to kidney failure. So far- my kidney function is in normal range.

October 7, 2025
MyMyelomaTeam

An increasing creatinine level while on Bortezomib (Velcade) treatment should be discussed with your healthcare team promptly. Since you're not currently on steroids, your doctor may consider adding high-dose dexamethasone to your treatment plan, as this combination has shown significant improvement in kidney function for Show Full Answer

An increasing creatinine level while on Bortezomib (Velcade) treatment should be discussed with your healthcare team promptly. Since you're not currently on steroids, your doctor may consider adding high-dose dexamethasone to your treatment plan, as this combination has shown significant improvement in kidney function for many patients. Kidney function management is crucial for myeloma patients. Some key strategies include:

- Maintaining adequate hydration
- Monitoring and correcting calcium levels
- Adjusting treatment plans as needed
- Regular monitoring of kidney function

Your healthcare team may need to reevaluate your current treatment plan, especially since kidney dysfunction can significantly impact survival outcomes in multiple myeloma patients.

June 16, 2025
A MyMyelomaTeam Member

Awesome!

October 7, 2025

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