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Stage II MM, early in induction therapy. Does anyone have any recommendations about how to reduce the abdominal pain?

April 28, 2025
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A MyMyelomaTeam Member

Robert, ensure that they give the velcade shot very slowly. I am not knowledgeable about darzalex.

April 29, 2025
A MyMyelomaTeam Member

I ask that the nurses push my Darzalex straight in, not at an angle. They use a butterfly needle and I hold it steady. Velcade burns and hurrts going in. My nurse would fill a glove with ice and ice my belly before my shot. That helped so much!! That being said, I did get abdominal cellulitis from a Zarxia shot. So, let check your belly and certainly let them know if you run a fever.

April 30, 2025
A MyMyelomaTeam Member

I found the injection would sting as it went in the nurses would alternate which side of my rather flabby stomach they injected the odd time ended up with bruising.

April 30, 2025
MyMyelomaTeam

Yes, abdominal pain from injection sites is a common experience with these medications. One helpful tip that has worked for other patients is to consider changing the injection site location. Some patients have found relief by receiving their Velcade injections below the shoulder area instead of the abdomen, reporting fewer Show Full Answer

Yes, abdominal pain from injection sites is a common experience with these medications. One helpful tip that has worked for other patients is to consider changing the injection site location. Some patients have found relief by receiving their Velcade injections below the shoulder area instead of the abdomen, reporting fewer side effects and less pain. Before trying any pain management solutions, it's important to discuss your symptoms with your doctor. They can evaluate if adjustments to your treatment plan are needed. Some patients find relief using hot or cold compresses to help manage injection site discomfort. Your healthcare team might also recommend alternative pain management strategies since Tylenol isn't providing adequate relief. If you're experiencing severe discomfort, don't hesitate to contact your healthcare team right away. Never adjust or stop medications on your own, as this could impact your treatment's effectiveness. Your doctor can work with you to find the best solution while maintaining your treatment schedule.

April 28, 2025
A MyMyelomaTeam Member

THANK YOU ALL VERY MUCH!!

April 30, 2025

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