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A MyMyelomaTeam Member asked a question 💭
Longmont, CO
April 22, 2025
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Yes, there is typically a relationship between M spike and plasma cells, though it's not always a direct correlation. M protein (M spike) is produced by abnormal plasma cells, so when there are more cancerous plasma cells present, they generally produce more M protein.

In conditions like early myeloma, M protein levels may Show Full Answer

Yes, there is typically a relationship between M spike and plasma cells, though it's not always a direct correlation. M protein (M spike) is produced by abnormal plasma cells, so when there are more cancerous plasma cells present, they generally produce more M protein.

In conditions like early myeloma, M protein levels may be lower (less than 30 g/L), while advanced myeloma can show levels over 70 g/L, reflecting a higher burden of abnormal plasma cells. However, it's important to understand that M protein levels are just one way doctors monitor myeloma. Your healthcare team will look at multiple factors, including imaging tests, genetic tests, bone marrow biopsies, and other blood tests to get a complete picture of your condition and how well treatments are working.

April 22, 2025

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