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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
April 18, 2025
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A MyMyelomaTeam Member

But if my M protein level is unchanged, what accounts for my low gammaglobulin level? Something other than MM or MGUS?

April 18, 2025
MyMyelomaTeam

No, that would not be a correct assumption. In myeloma and MGUS, doctors carefully monitor protein levels in the blood, including immunoglobulins (gammaglobulins), as changes in these levels can indicate disease progression. The presence and amount of abnormal proteins (M proteins) in the blood is one of the key markers Show Full Answer

No, that would not be a correct assumption. In myeloma and MGUS, doctors carefully monitor protein levels in the blood, including immunoglobulins (gammaglobulins), as changes in these levels can indicate disease progression. The presence and amount of abnormal proteins (M proteins) in the blood is one of the key markers doctors use to assess disease status.

Regular blood tests to evaluate the type and amount of abnormal proteins are an essential part of monitoring both conditions. These tests help determine if the condition is stable or progressing. For people with MGUS, doctors typically recommend blood and urine tests every 6-12 months to check for any changes in protein levels. The frequency of monitoring may increase if there are signs of progression. These regular screenings are crucial as about 20 percent of people with MGUS will eventually develop multiple myeloma.

April 18, 2025

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