I had issues with Pomalyst also,on it not even 2 weeks, my cancer center ran out of options for me and so I had to go to Dana Farber to find a option for me,which was techvayli,which has been a life saver for me
I was on Pomalyst and my ALT and AST went way up. My oncologist stopped Pomalyst right away. Was only on it for two weeks. Not only did my ALT and AST go high, but developed a rash all over my body and had trouble breathing. I went to the Cancer center for my weekly treatments and they took one look at me and called the doctor right away. A soon as I was finished with the treatments I had to go to the doctor's office.
Elevated liver enzymes (ALT and AST) can occur as side effects of myeloma treatments. While the specific levels you mention are concerning, it's important to report these elevated numbers to your healthcare team immediately. Carfilzomib (Kyprolis) and other proteasome inhibitors can affect various organs, including the Show Full Answer