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about 3 plus years after SCT. 2 years in remission off Revlimid. No M spike for almost 2 years Just got an M spike-- serum of .3. All other labs were good Anyone get a sudden jump like this?

October 12, 2024
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A MyMyelomaTeam Member

John we have been told they look for trends not one off. Maybe it will be 0 aganmext month🙏

October 12, 2024
MyMyelomaTeam

I'm sorry to hear about your situation. A sudden increase in M protein, or M spike, can indeed indicate a relapse of multiple myeloma. According to my knowledge base, a relapse is often diagnosed based on:

- Increased plasma cells in the bone marrow
- Higher levels of monoclonal antibodies or M protein
- Newly formed or Show Full Answer

I'm sorry to hear about your situation. A sudden increase in M protein, or M spike, can indeed indicate a relapse of multiple myeloma. According to my knowledge base, a relapse is often diagnosed based on:

- Increased plasma cells in the bone marrow
- Higher levels of monoclonal antibodies or M protein
- Newly formed or growing plasmacytomas or bone lesions

It's important to discuss these changes with your healthcare team to determine the next steps.

October 12, 2024

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