Ativan helps…

Todd, I had to take the Dex once a week. For me getting up really early on that day, and taking the Dex right away seemed to help. If I took it later, I had difficulty sleeping that night. Initially, I was taking ten 4mg tablets once per week. When I had symptoms similar to yours, my oncologist cut me back to 5 tablets.

Hi Todd, exercise does help. Strength training can help with the muscle wasting. I took Xanax to help with anxiety. I also took Ambien to help me sleep. They put me on Prednisone for a few months. It doesn't affect the brain quite as much. Talk to your doctor about lowering the dose or a different schedule. It's a difficult drug to take. It does help to get the myeloma under control. 💗

I have insomnia the day I take Dexamethasone otherwise I don’t have any other side effects.

The dexamethasone is a tough drug. I only take it once a month for 3 days with the Darzalex injection. Initially I was on 20mg dex for 2 days, day of and day after the injection, but by day 4 I would "crash" and sleep all day and just be a zombie days after. My dose was decreased to 20mg day 1, 12mg day 2 and 8mg day 3. Much more tolerable. I couldn't image taking it every day!