Has Anyone Had Side Effects From Darzalex Faspro? | MyMyelomaTeam

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Has Anyone Had Side Effects From Darzalex Faspro?
A MyMyelomaTeam Member asked a question 💭

Ron's had 6 of 8 weekly 4+ hour Darzalex infusions. Hearing about the faspro injection, we're wondering now why his oncologist chose the infusion route. We'll be asking about his reasoning at the next appointment, but interested in getting team input meanwhile.

posted September 8, 2022
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A MyMyelomaTeam Member

Hi Ron - I received Darz FasPro Shots. During my treatment, there were 4 of us getting it. My Nurse said of the four, I had the very least amount of peeling of my skin at the injection site. I guess the others must have had a quite a bit for her to make the comments that she did. On occasion, I had a slight redness around it but it went away and never bothered me. Each week they would inject at one side and then the next, to the left or right of my belly-button. They need to pull the skin and make a fold so they were injecting under the surface of the skin, not into the muscle under the skin. I've heard of a case where someone was injected too close to the belly-button and it was very bad - keep an eye-out for that. Make sure you have an experienced person and try to only have that person do the shots. They gave me Velcade and Darz FasPro shots on Monday and Velcade on Thursday. They always made sure to switch the sides every Monday for the Darz FasPro shot. I'm really glad I never had to do the IV. When they did the Darz FasPro, for the first few weeks it was a 90 minute monitoring and then it went to 30 minute monitoring for a reaction. Never had one at their office. Did have neuropathy response but I expect it was the Velcade.
Good luck with that and All the Best.

posted September 8, 2022
A MyMyelomaTeam Member

When it was burning due to too fast, I said - please slow down. My Nurse asked that I always inform how it was going.

posted September 16, 2022 (edited)
A MyMyelomaTeam Member

Hi Joan - I went looking for the Article again. It was difficult to locate so here's the Link. This Forum has excellent Articles. I've continued to learn plenty from them.

Link to Immunotherapies:
https://www.mymyelomateam.com/resources/immunot...

posted September 11, 2022
A MyMyelomaTeam Member

Hi Joan - search this forum for immunotherapy. Darzalex & FasPro targets MM cancer cells with CD38. My FISH report stated my MM had CD38. I expect that’s why I had such a quick response to Induction since I had DarzFP + RVD.

There are other immunotherapies when CD38 is not part of the MM cell structure.

Reading the article, immunotherapy is a great advancement over traditional chemo. It also had links to other published articles.

posted September 10, 2022
A MyMyelomaTeam Member

My husband is on a 24 month trial. He’s in 5 months now. Fatigue, jitters. Brain fog. And tired. Pale after iv chemo. I never know what’s right and wrong. It’s a lot to learn

posted September 10, 2022

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