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Other Options Rather Than Stem Cell Transplant

Other Options Rather Than Stem Cell Transplant

Oncologist preparing for stem cell transplant for my husband, but after careful research, he does not know if he wants to undergo such a grueling procedure which has no guarantee of remission. He is doing quite well with his weekly chemo treatments which have astounded his doctors. Has anyone used alternative measures other than stem cell transplant, and instead decided on another version of treatment. We are so overwhelmed and indecisive about this.

A MyMyelomaTeam Member said:

Hi Donna6,

I did not get a SCT. I’m now MRD Negative (no measurable cancer based on the newer testing method from clonoSEQ)

I started from a very bad place - 80% bad plasma, 5915 IgA (400 max normal) and many other bad values.

Prior to treatment, we visited Johns Hopkins (JH) for a second opinion. He said that I should get Darzalex FasPro (Darz) with my First Line Treatment with + RVD. He said it would result in a deeper and faster remission.

Based on the above regime, my Labs were back to normal after 6 weeks (my oncologist was amazed). They said I was in remission at that point and continued induction for another 6 weeks. Then they said I was ready for my SCT.

Had a telehealth with JH about the SCT process. He said now or 3 years from now made no difference to my long term survival rate. I elected to postpone. I went directly to maintenance meds - lower levels & less frequent. Two months later I dropped two of my meds due to bad neuropathy.

Another two months later, they tested me for MRD. My results were MRD Negative.

If his Labs are normal then postponing may be a viable option. I was so weak from induction, I wasn’t willing to consider a SCT for at least a year. Now that I’m Negative, I have no plans to get one. The purpose of a SCT is to get you to Negative. Negative is Negative - doesn’t matter how you get there.

Now that I’m Negative, my Doc placed me on Monitoring mode with no MM Maintenance Meds. Based on the MRD-SURE Report (google search), I plan to stay on Monitoring mode until my Labs indicates a need.

During induction I needed a walker and transport chair. Just finished 4 weeks of going to the gym (will continue daily). I’m stable on my feet again and getting stronger. Planet Fitness (and others) are free to seniors with Silver Sneakers insurance.

edited, originally posted 5 days ago
A MyMyelomaTeam Member said:

Thank you and so thrilled for you that you are doing well! Your comments have lifted our spirits so much. There is HOPE!

posted 5 days ago
A MyMyelomaTeam Member said:

Hi Donna6,

I so hope he has a quick, easy and complete and lasting remission.

My Consulting Doc at JH mentioned they’re seeing 20% getting similar results to me when their initial treatment was the same regime.

However one gets to normal Labs and remission is fine.

I expect that after my 12 weeks of induction I wasn’t MRD Negative, since I still had a small MSpike of 0.1. After being on maintenance meds for 4 months, it was then that they tested my MRD. My next Labs showed no MSpike for the first time. This provided me a secondary confirmation of my Negative status.

posted 5 days ago
A MyMyelomaTeam Member said:

I agree.we are taking this one step at a time and not feeling pressured into doing anything yet. My husband doing well.with.his treatments right now and down the road and at present.researching any other options. Happy to hear you're counts are good. Blessings and prayers to you. KEEP FIGHTING!

posted 9 days ago
A MyMyelomaTeam Member said:

I'm curious stem cell treatment keeps coming up with me also and my blood count seems well. why would you or myself go that route if what we're doing now is ostensibly working?

posted 9 days ago
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