My oncologist gave me antibodies shots EVUSHELD if you are unable to get an MRNA vaccination. There are so many questions regarding vaccinations applicable to recent Omnicron variants, but I believe the antibodies may help?Ask your oncologist about vulnerability due to your clinical trial treatments and antibodies. Your clinical trial is very important to consider too.
Your question really was about Covid isolation so I will let you know what I did. I kept my mind occupied by reading , a diet , exercise according to my physical capability, walks may be your choice, music , cooking. We socialized with safer folks and family. But do make sure you are discussing your vulnerability with your oncologist and are not overly fearful. I have never had Covid , but acted according to local case levels. I went on vacation in a warm climate outdoors and did well as the location had numerous precautions at the time in October.
Be thoughtful in consideration of your particular situation, but not fearful.
I hope you get through this challenging choice.

I was allowed to get the covid shot at 100 days then at 180 days I got my first set. Of shots. I haven't had the second set yet because of me being sick
I'm supposed to get the second set Monday and get back on track. If you are sick they won't be able to give you the vaccines.

I started my childhood shots at 180 days . The covid shot was given at 100 days and I had round 3 of the childhood shots last month. I am now taking antibodies drip to help me with dealing with fighting off getting sick.

I will get my third round of childhood vaccines soon. This is an old question. Thank you to everyone that answered!

We all have to fight off fatigue , melancholy, and sadness from Covid concerns and of course our Multiple Myeloma or medications issues. Finally, our weather is warming things up , less winds , cold and longer daylight helps. Anyways to enjoy the outdoors , walks helps. Have you spoken to your oncologist about getting a Covid EVUSHELD antibodies shot or booster to reduce any Covid concern? That can relieve you of the stress or worry about Covid too. Try to think of personal strategies that match your situations and focus on positive ideas to improve your quality of life.
I just am getting out of a long term “funk” , fighting off variations in neuropathy and insomnia so I kept fighting and it seems to be getting better. Never give up. You can persevere. Hope things improve. Take care and keep in touch.