Zometa is a prescription drug approved by the Food and Drug Administration (FDA) to treat people with multiple myeloma. Some doctors may also prescribe Zometa for people who have monoclonal gammopathy of undetermined significance (MGUS) or smoldering myeloma and signs of osteoporosis. Zometa may be referred to by its drug name, Zoledronic acid.
Zometa is a bisphosphonate. Bisphosphonates are believed to work in cases of myeloma by reducing the activity of osteoclasts, the cells that break down bone. Bisphosphonates are believed to work by reducing the number of bone lesions, thereby improving pain and lowering the risk for fractures.
How do I take it?
Zometa is administered by intravenous (IV) infusion every three to four weeks.
Zometa comes in vials of concentrate or prepared solution.
The FDA-approved label for Zometa lists common side effects including fatigue, fever, trouble breathing, nausea, vomiting, constipation, and bone pain.
Rare but serious side effects listed for Zometa include osteonecrosis (death of bone tissue) in the jaw, atypical femoral (upper leg) fractures, fetal harm, hypersensitivity reactions, and severe bone, muscle, or joint pain.
For more details about this treatment, visit:
Zometa – FDA prescribing information
Drug Therapy for Multiple Myeloma – American Cancer Society