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Been on chemo for just over a year, started with 4 weekly blood tests and reviews, and for the last 6 months, on 8 weekly. They have also cancelled my dexamethsone and cotrimoxazole while my Lenalidomide remains at 10mg.

October 22
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MyMyelomaTeam

What does having almost non-existent paraproteins mean for your myeloma treatment going forward?

This sounds like really encouraging news! Paraproteins (also called M proteins) are produced by myeloma cells, so having almost none detected in your blood suggests your treatment is working very well. This kind of response is Show Full Answer

What does having almost non-existent paraproteins mean for your myeloma treatment going forward?

This sounds like really encouraging news! Paraproteins (also called M proteins) are produced by myeloma cells, so having almost none detected in your blood suggests your treatment is working very well. This kind of response is exactly what the treatment aims for.

The changes to your care plan seem to reflect this positive progress:

- Less frequent blood tests (4-weekly to 8-weekly) suggest your team is confident in your stability
- Stopping dexamethasone likely means the steroid support is no longer needed at this stage
- Stopping cotrimoxazole (an antibiotic used to prevent infections during intensive treatment) suggests your infection risk has reduced
- Continuing lenalidomide at 10mg is a common maintenance therapy approach to keep myeloma suppressed Lenalidomide maintenance is well established for keeping myeloma at bay after a good response. It's generally well tolerated, though it's still worth monitoring for changes in blood counts and any signs of blood clots.

Keep attending those 8-weekly reviews and let your team know about any new symptoms. The goal now is maintaining that response for as long as possible. Your care team will continue tracking your paraprotein levels to catch any changes early.

October 22

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