Mine did, but most do not.
October 5
Yes, MGUS can progress to smoldering multiple myeloma (SMM), though it doesn't always happen. Think of them as steps on a ladder — MGUS is the first rung, SMM is the middle, and active myeloma is the top.
Here's a quick breakdown of the progression risk:
- People with MGUS have about a 1% chance per year of progressing to Show Full Answer
Yes, MGUS can progress to smoldering multiple myeloma (SMM), though it doesn't always happen. Think of them as steps on a ladder — MGUS is the first rung, SMM is the middle, and active myeloma is the top.
Here's a quick breakdown of the progression risk:
- People with MGUS have about a 1% chance per year of progressing to myeloma
- If MGUS does progress, it typically moves to SMM first before becoming active myeloma
- Not everyone with MGUS will develop SMM or myeloma For those who do reach SMM, the progression risk to active myeloma is higher but decreases over time:
- First 5 years: ~10% chance per year of developing active myeloma
- Years 5–10: drops to about 3% per year
- After 10 years: around 1% per year
Regular monitoring with blood and urine tests is the key tool doctors use to keep an eye on any changes. Staying on top of follow-up appointments is really important.
October 5
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