Myeloma is classified into three stages using the Revised International Staging System (R-ISS). Staging is based on blood protein levels, genetic changes in cancer cells, and other factors — not on how far the cancer has physically spread like some other cancers.
Here's a quick breakdown of each stage:
- Stage 1 – The Show Full Answer
Myeloma is classified into three stages using the Revised International Staging System (R-ISS). Staging is based on blood protein levels, genetic changes in cancer cells, and other factors — not on how far the cancer has physically spread like some other cancers.
Here's a quick breakdown of each stage:
- Stage 1 – The earliest stage. Cancer cell levels are low, and some people may have no symptoms yet. Doctors may recommend monitoring rather than starting treatment right away.
- Stage 2 – A middle stage where the disease is more advanced than Stage 1 but not as severe as Stage 3. Symptoms like bone pain, fatigue, and frequent infections may appear. More intensive treatment is often needed.
- Stage 3 – The most advanced stage. Protein markers in the blood are very high, and cancer cells may show aggressive genetic changes. Symptoms can include severe bone damage and poor kidney function.
One MyMyelomaTeam member summed it up well: *"Myeloma staging has such different rules — it is tough to learn everything."*
It's worth knowing that Stage 1 can remain stable for years, while Stage 3 tends to progress more quickly. No matter the stage, sticking to a treatment plan and keeping open communication with your care team makes a real difference.
August 20
Join
Your Privacy Choices
