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Is there a relationship to having had COVID to the development of multiple myeloma?

A MyMyelomaTeam Member asked a question 💭
Butte, MT
December 25, 2025
 · 
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Viral Infections and the Risk of Multiple Myeloma: What We Know Read Article...
A MyMyelomaTeam Member

Thank you

December 29, 2025
A MyMyelomaTeam Member

I have always wondered this as well. My husband got COVID in April 2021, then again in April 2022, and was diagnosed with MM at the age of 52 in June 2024, which they said was very young for this disease. I wonder if COVID accelerated it and a fall he experienced that hurt his back in Feb of 2024 ignited it. We'll never know for sure. He just had a Bone Marrow Transplant in June 2025, then got COVID again in Sept 2025, so I'm really hoping COVID didn't mess him up. I noticed an increase in his Kappa Light Chain numbers in Sept, and again in Dec. I'm hoping it was to help his body recover from COVID in addition to building back his immune system. We'll see next month when his numbers are pulled again.

December 28, 2025
A MyMyelomaTeam Member

Dave,
I had Covid in early 2020 and was diagnosed with MGUS in late 2020, then later Smoldering MM. I think Covid might have accelerated it, but I have had low White Blodd Cells since 2011 when I had my first CBC.
Paula🌹

December 27, 2025
A MyMyelomaTeam Member

Thank you. The reason I asked that question is because my multiple myeloma diagnosis seems to coincide with having had COVID.

December 25, 2025
MyMyelomaTeam

Is there a relationship between having had COVID-19 and developing multiple myeloma?

Recent research from 2024 suggests there may be a connection. The study reported that SARS-CoV-2 infection (the virus that causes COVID-19) might be a risk factor for developing myeloma due to its effects on the immune system.

However Show Full Answer

Is there a relationship between having had COVID-19 and developing multiple myeloma?

Recent research from 2024 suggests there may be a connection. The study reported that SARS-CoV-2 infection (the virus that causes COVID-19) might be a risk factor for developing myeloma due to its effects on the immune system.

However, it's important to understand that this is emerging research. Having COVID-19 doesn't mean you'll develop myeloma. Scientists believe multiple myeloma develops from a combination of factors, and viral infections are just one possible risk factor among many.

Other risk factors for myeloma include:
- Age (most common in people over 65)
- Race (Black people have higher risk)
- Family history
- Exposure to certain chemicals or radiation
- Having MGUS (monoclonal gammopathy of undetermined significance)

If you're concerned about your risk factors, including past COVID-19 infection, it's worth discussing with your healthcare team. They can help assess your individual situation and determine if any monitoring or preventive measures are appropriate.

December 25, 2025

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