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December 22, 2025
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What happens after transplant and consolidation therapy without maintenance therapy?

After a stem cell transplant and consolidation therapy, maintenance therapy is typically recommended to help keep myeloma from returning. Without maintenance therapy, there's a higher risk of the cancer coming back sooner.

Research shows Show Full Answer

What happens after transplant and consolidation therapy without maintenance therapy?

After a stem cell transplant and consolidation therapy, maintenance therapy is typically recommended to help keep myeloma from returning. Without maintenance therapy, there's a higher risk of the cancer coming back sooner.

Research shows that maintenance therapy with lenalidomide can sustain remission for about 57 months in 50 percent of people after a stem cell transplant, compared to only 30 months without maintenance treatment.

Why maintenance therapy matters:

- Helps prevent cancer cells from returning
- Extends the time in remission
- Is considered standard care after transplant

If you're not on maintenance therapy after your transplant and consolidation, it's important to discuss this with your doctor. They can explain whether maintenance therapy would be beneficial in your specific situation or if there are reasons why it wasn't recommended for you.

Some people may not receive maintenance therapy due to side effects, personal preferences, or other medical factors. Your healthcare team can help you understand the risks and benefits of starting or continuing maintenance therapy.

December 22, 2025

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