How long until he can get into remission
I've recently found a simple Blood test that I intend to get at my next monthly Monitoring Labs (Dec 3rd) - It shows a Genetics factor that we're born with. We can't add it and we can't lose it.
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For the NK-92 type of status of V/V genetics Quest Diagnostics
Test: "CD16A (FCGR3A) F158V Polymorphism Analysis"
Quest Test Code: 34493
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This company - https://cssifm.org/patients/
Has a tech that they add to a person's Treatment
It's referred to as HANK - it Boosts a person's NK-92 Killer Cells during a Chemo Treatment to enhance the Treatment.
Watch the first Video regarding the woman that recovered from Stage 4 breast cancer due to the inclusion of NK-92. Up until this, all else had failed. All the other Videos are good as well.
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So here's the Deal - 10% to 15% of people Naturally have their own Natural Killer Cell Immunity that is Equal to getting NK-92 Enhancement.
The simple Blood Test - Quest Test Code: 34493 - identifies the Genetic Level of a Person. You're born with it and you can't add to it or ever lose it.
The Test Results are graded as - V/V (NK-92 equal - 10% to 15% of people), V/F (good), F/F (not good but NK Cells availability can be enhanced with Diet & Supplements).
If my Quest Test Code: 34493 returns as V/V, it almost Completely Explains my Instant Recovery in 2021, with Induction of DarzFasPro+RVd.
DarzFasPro Requires Natural Killer Cells for it to work and Kill MM.
My Lab Records Prove to me I was MRD Negative (from 5.2 MSpike to 0.03) and producing Completely Normal Blood levels in 5 weeks (RGB, WBC, Kappa/Lambda, etc), in 2021 - starting from my Stage 2, t4;14, 5915 IgA Kappa (all poor indicators).
I'll know as of my next Labs - this would make so much sense. Yes, maybe the Case of my Recovery is unusual but if my Genetics are V/V, this is Really Important for people to be able to "Know their Potential Before Treatment" and therefore - Treat As Needed.
Sheryl, we all respond differently to these drugs. Some people get into remission pretty quickly. Others take much longer. Most people have to be on maintenance therapy at least for some time after initial treatment. Depending on his myeloma genetics he might have to be on therapy for a long time to keep his myeloma at bay.
Part 2:
They need a better understanding of the MM Side effects (I was very actively complaining in 2021) and the details of what the Labs actually reveal that can Justify a Reduction of MM Treatment Meds. In 2021, I completely Trusted their Judgement, only to realize they simply follow the Standard of Care rather than perform a Person-by-Person Evaluation of their Individual Response.
My Consulting John Hopkins Onc once told me that they Don't Reduce a Person's Treatment Meds if they Respond, they simply Increase them when they they stop responding to the current Maintenance/Treatment.
The Problem with that mindset is it continues to leave a person significantly Immune Compromised and very venerable to life threatening infections.
DarzFasPro depletes 90% of your Natural Killer Cells (NKCells) within the first hour or two of the First Injection - our NKCells are our Innate Immune System that are critical to our defense against serious infections - both bacterial & viral.
Please know that DarzFasPro can Always show a False MSpike - from 0.1 to 0.2 in the SPEP Report. Get the Lab Test # 123213 - IFE, Dara-Specific. This will cancel the False MSpike from DarzFasPro.
If they try to tell you that - If you're IgA that this Test does not pertain to you - Don't believe them - they're wrong - they're simply repeating the info on the DarzFasPro website which Does Not take into account that the SPEP is showing the MSpike Value as a total from All Ig's, without the ability to determine which Ig is responsible for the Value.
The reason I mention this is when they see a MSpike of 0.1, they assume you're still MM Active and Not In Remission.
Though in 2021, I was Stage 2 - t4;14 high risk, 5915 IgA Kappa. As I've come to learn about the details of my Labs and MM Markers, I gone back and reviewed All of my Labs and have been able to determine that I was actually in Complete Remission within 5 Weeks of Starting my Induction in 2021.
Unfortunately, they used their misunderstanding of my persistent False DarzFasPro 0.1 MSpike to justify the 3 months of Induction and 4 months of reduced Maintenance, that once they correctly tested me with the #123218 Lab test (at my continued request), it confirmed I was in Complete Remission and then they did the Blood Sample clonoSEQ test that proved I had No Caner Per Million Cells Tested - At which time, I immediately stopped All MM Meds and continue to remain on None, now 4 years later - also I never collected my Stem Cells (due to the chemicals involed) and of course I've not had a SCT (due to the long term damage of the bone marrow microbiome).
My complaint about the needless continuation of the Induction with DarzFP+RVd is the permanent and persistent neuropathy that just never had to happen. Had I not had the t4;14, they would not have used Velcade - the most common cause of permanent neuropathy.
I needed the MM Treatment Meds in 2021 but I did not Need them to the point of the permanent damage they caused.
End Part 1:
How long does it typically take to achieve remission with treatment for myeloma?
It's wonderful that your husband's numbers are looking so encouraging after starting his second cycle! The timeline to remission varies significantly from person to person, depending on how well someone responds to treatment.
Some people Show Full Answer