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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
September 25, 2025
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A MyMyelomaTeam Member

I’m all in favor of not having radiation. I did have it on my lower back and the cancer is gone but the pain isn’t. I’ve heard that radiation also changes the composition of your bones and not in a good way. If you have the choice to just try chemo I think that would be best. Less is sometimes more. Do ask your doctor as a lot of times they won’t tell you about options unless you challenge them. Wishing your husband all the best.

September 25, 2025
A MyMyelomaTeam Member

I had kyphoplasty to repair mine too. I think it was a great choice.

September 25, 2025
A MyMyelomaTeam Member

Always get a second opinion from an Interventional Radiologist. Twice mine recommended against Radiation. He was right in both cases, for my original L4 Fracture, repaired with a Kyphoplasty, and my Bone Lesion Tumor 2 years later, recovered with just a brief treatment of MM Meds.

September 25, 2025
MyMyelomaTeam

Yes, radiation therapy can be an effective treatment option for vertebral fractures and bone lesions in myeloma. It works by
• Shrinking tumors that may be causing pain
• Treating osteolytic lesions
• Strengthening affected bones
• Providing pain relief

A MyMyelomaTeam member shared positive results when radiation was used Show Full Answer

Yes, radiation therapy can be an effective treatment option for vertebral fractures and bone lesions in myeloma. It works by:
• Shrinking tumors that may be causing pain
• Treating osteolytic lesions
• Strengthening affected bones
• Providing pain relief

A MyMyelomaTeam member shared positive results when radiation was used to treat lesions pressing on nerves in their lower back, reporting that after 10 treatments "it worked!" Common short-term side effects of radiation treatment may include:
• Fatigue
• Swelling
• Nausea
• Skin changes similar to sunburn

These side effects typically resolve within 6-12 months after treatment, though they can occasionally last up to 2 years. Your husband's doctor will determine the best radiation schedule based on factors like the size and location of any fractures or lesions found.

September 25, 2025

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