Yes, multiple myeloma commonly causes kidney problems. Up to half of people with multiple myeloma develop kidney issues, and about 10% develop kidney failure severe enough to require dialysis.
The main cause is that myeloma cells produce too many abnormal antibody proteins that enter the bloodstream. These proteins can Show Full Answer
Yes, multiple myeloma commonly causes kidney problems. Up to half of people with multiple myeloma develop kidney issues, and about 10% develop kidney failure severe enough to require dialysis.
The main cause is that myeloma cells produce too many abnormal antibody proteins that enter the bloodstream. These proteins can clog the kidney's filtering tubes, causing inflammation and damage to kidney tissue. Risk factors that can increase the chance of kidney problems include:
- Having other conditions like diabetes or high blood pressure
- Smoking
- High blood calcium levels
- Certain medications including NSAIDs
- Not drinking enough water
- Advanced age
- More severe myeloma
Staying hydrated by drinking 2-3 liters of water daily is important for kidney health. Always consult your doctor before starting any new medications, as some can worsen kidney function.
July 20, 2025