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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
March 1, 2025
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A MyMyelomaTeam Member

I know the higher the number is a judge of outcome. Make sure you see a MM specialist to explain so you can understand the results.

March 2, 2025
A MyMyelomaTeam Member

Hi Mike,
I have Smoldering MM and my Beta-2 M is 2.3 mg/L. What I understand it to be is a tumor marker or it reflects the cellular immune system-which I read somewhere online. When the kidneys are not working, it accumulates in the blood. I’m not sure what your Creatinine numbers are. Mine are on the high end for women. Beta-2 M International Stage I is less than 3.5 mg/L or (2.5 +-0.87), Stage II 3.89 +- 1.82, Stage III 6.46 +- 3.31. One number does not define your diagnosis. Important labs are M Protein, Kappa/Lambda ratio, and Plasma cells. The next I think are Creatinine, Hypercalcemia, and Lesions on scans. If your Hematologist/Oncologist does not specifically specialize in MM, you need a Second Opinion, which is the best thing you can do. My first two Oncologists knew less about my MGUS than I did. I changed Doctors and went to a MM Specialist and they did another Bone marrow biopsy and I changed to Smoldering MM. A Specialist will work with your local doctor, if you don’t live near them. I highly recommend Dr Brandy’s book “Beat Back Cancer Naturally.” TheMMRF.org has lots of information on it’s site. This site under “Resources” is great too.
Paula🌹

March 1, 2025
A MyMyelomaTeam Member

Thanks for additional info

March 1, 2025
MyMyelomaTeam

It's understandable to feel concerned about test results that are outside the normal range. While MGUS itself is not cancer, doctors carefully monitor patients through regular blood tests to watch for any changes that might indicate progression.

MGUS has a relatively low progression rate - about 1% per year chance of Show Full Answer

It's understandable to feel concerned about test results that are outside the normal range. While MGUS itself is not cancer, doctors carefully monitor patients through regular blood tests to watch for any changes that might indicate progression.

MGUS has a relatively low progression rate - about 1% per year chance of developing into multiple myeloma. Most people with MGUS never develop myeloma and don't require immediate treatment. The best approach is to follow your doctor's recommended monitoring schedule. They will typically suggest blood and urine tests every 6-12 months, with the frequency based on your individual risk factors. This regular monitoring helps catch any changes early.

Rather than worrying, focus on attending your follow-up appointments and having open discussions with your healthcare team about any concerns. They can best interpret your specific test results and adjust monitoring as needed.

March 1, 2025

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