Samar I'm really sorry to hear your transplant didn't work, that is rough news. I am so hopeful for CAR-T, this disease is a waking nightmare and I am hating how many terrible drugs they make us take before getting to the only therapy that really seems to have long term hope to be done with that. Best of luck to you.

my transplant last only 6 months ,my m spike start rising again now, car t cell maybe in the future

Thanks Samar for your info. So your Dr. is counting the chemo you had before your stem cell transplant as a line of therapy and the transplant as a seperate line. You have had way more variety of drugs already than I have. I started with VRd like you, but had to stop Revlimid due to severe allergic reaction. It was replaced with Cytoxin which is non specific and doesn't count. I believe I will have to try Darzalex to meet the Anti-CD38 requirement and perhaps Pomalyst as an IMiD because I was so allergic to Revlimid. I hated dexamethasone and wish I could avoid anymore of that one. Carfilzomib sounds like a nightmare too but I think I have done enough Proteosome Inhibitor with all the Velcade I have had so maybe not that one either.
Will you go for the CAR-T? What are you on after transplant and how successful was it?

I read that out of (Phone number can only be seen by the question and answer creators) eligible only 10 received it. It also may cause other cancers.

hannahleah , I will share with u how I'm eligible for car t cell now, when I first diagnosed I was on:velcade dexamethasone revlimid so that's my first line, after 2 months velcade give me eyes problem so they changed to carfilzomib so carfilzomib dexamethasone revlimid that's my second line, on September 2022 they add darzalex faspro to carfilzomib dexamethasone revlimid that's my third line, may 2023 stem-cell transplant that was my fourth line , my doctor told me that I'm eligible now to car t cell if I want