Depending on what you want, stem cell harvesting after one dose of chemo, then re-administering your own cells can work for a long time. My high school friend had 80% of her bone marrow affected by MM. She had the stem cell therapy last May. She didn’t have a lot of side effects though some people do. She is still doing well, able to work in her garden. I am at the smoldering stage unless the next testing shows something different. My oncologist follows me every 3 months with a PET scan, 24 hour urine and bloodwork. I had a plasmacytoma on my scalp which resolved with radiation. It’s a given that MM follows. Honestly you have to decide what you want to do. Nothing is mandatory and I hope this helps.

I'm not sure I understand your question. MM patients get chemotherapy and other treatments to put the MM into remission, maybe for several years. And then when your MM comes back, you do a different treatment to put it into remission. That gives you time with family, maybe you can work, go on vacations, have hobbies, attend family events like reunions. And for radiation, I had it for soft tissue tumors. It did help shrink them some. They were in an area that caused a lot of pain. But shrinking helped reduce the pain. I don't even get much remission but I keep doing the treatments they recommend because it gives me more good, positive time with my family. Good luck to you.