Doc recommended Kyprolis for consolidation therapy along with Darzalex and Dexamethasone.
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Mark and Howeler - Thanks for the hug.
Marryann2 praying for your husband that things get better for him.This disease treatment is no joke
Thanks Donna and Howeler. My husband takes his blood pressure at least twice a day now. He had a- fib for a week after stem cell transplant that lowered his ejection fraction. After he was stable and released from the hospital, he saw his home town cardiologist and had an echocardiogram about a week later. He was back to his baseline of 50%. A second echocardiogram about 2 weeks ago also showed stable at 50%. He had a St Jude loop recorder inserted about 3 weeks ago to monitor a-fib and no events have occurred. The loop recorder will also pick up any increases in heart rate. Cardiologist also recommended to get another echocardiogram after a month of Kyprolis even if he has no symptoms. He had 2 percent plasma cells after stem cell. Has had no m-spike since last May 2023. His serum Quantitative Kappa light chains 37.1,
Lambda free light chains 3.6, kappa lambda ratio 10.31. That is similar to what he had before the stem cell transplant. He has del 17 p53 high risk. Genetics are now normal on FiSH after stem cell. He’s never had Darzalex or Kyprolis. My husband didn’t want more Velcade. His feet are numb and worried about worsening neuropathy. She wants him to do 6 cycles and then check. He is 74 years. I’m praying this will be okay. Of course, I’m scared.
Been on Kyprolis since May 2022. First treatment included Pomalyst and Dex. Reduced Kyprolis dosage after 6 months. Lasted until Sept 2023 and then lightchains hit the moon. Put back on full strength dosage along with Venexta and several antibiotics. Never had a problem with cardiac issues and neuropathy in toes has been minor since I started my MM journey. Only side effect I have now is getting sick after infusion of Kyprolis since going back full strength. That’s going to get reduced again. Hope this helps.