Hi Steveh - There’s plenty of info about C3 Curcumin at my Story @A MyMyelomaTeam Member.

My Doc was all in favor of me taking it. I started with 4,000mg daily and during the past year I’ve slowly upped it to 8,000mg daily.

I started with 80% bad marrow and 5915 IgA. Was back to normal Labs in 6 weeks, changed from Induction to Maintenance at 12 weeks (No BMT/SCT). At 7 months from beginning Induction I tested MRD Negative and was removed from All MM Meds (around 8 months ago). Just being Monitored with Labs and clonoSEQ MRD Testing.

DarzalexFasPro + RVD and C3 Curcumin throughout Induction. Reduced Induction Meds for Maintenance of 4 months but I dropped Dex & Velcade 2 months into Maintenance due to neuropathy.

Lookup MRD-SURE and MRD2STOP. They explain why I'm being Monitored without continuing MM Meds.

Mentioned Users

A MyMyelo...

I take it on advice from other cancer patients. I also take turkey tail mushroom and tart cherry. When I need a refil I’m getting a 5 mushroom blend. All from amazon. I was on chemo and revlimed from March to November. I’m in remission currently and on no meds. New blood work and doc apt end of month to see where I’m at. Did the supplements help idk but I’m going to stay on them

Larry2,
You are right. That’s what all the research says.

Yes high doses of curcumin can lower blood pressure (blood thinning maybe), It can also chelate some iron out of your stomach if you are trying to build your HGB take it on a empty stomach before going to bed. Also, build up slowly to high doses. It can cause some pretty good diarrhea if you go too fast. Your body can become use to it eventually if you go slow. NOT recommend for those with gallstones.

Do not get the impression that curcumin can make your myeloma go away. There seems to be evidence it can have a suppressing effect, though. It is important that your supplement is the C3 complex, has Bioperene (black pepper extract) for absorption and to make its bioavailability higher, otherwise it can just go right through you too quickly. Please read as much as you can.

Here's some links:
https://oatext.com/Long-term-follow-up-of-curcu...
(Read last conclusion paragraph). Curcumin Gets Positive Results in Small MGUS and Smoldering Study

https://journals.aai.org/jimmunol/article/171/7...
.... Conclusion: (last paragraph) Our results also indicate that curcumin can overcome dex resistance of MM cells:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC71....
Last Paragraph Conclusion:
Consequently, curcumin possesses the potential to impede myeloma activity and improve the quality of life in MM patients. Further randomized controlled trials should aim to elucidate and replicate the findings of this study.

Thus at age 78 and at MRD Negative at 10 to the minus 6 I have elected to use 6 grams of curcumin every day as maintenance instead of Revlimid. Doctors will not recommend using curcumin but I think you can well establish the case enough that they will not object, except for the reasons mentioned above.

Hope this helps on the curcumin issue. One more thing. Taking Tumeric is not the same. Curcumin is "extracted" out of the turmeric root.

Leland

I am taking eliquis and curcumin. I have upped my dose of curcuminC3 to 4000mg and trying to get to 8000mg. My heart doc didn't say anything about it, but maybe he didn't look at all the supplements I am on. My myeloma specialist said no harm but it could give stomach upset. There was a trial for MGUS/SMM patients using 8000mg curcumin. My doc said it is a cancer killer. I really wish I could get off of eliquis.