Leg weakness can be caused by something compressing the spinal cord. Has your husband had a MRI to see if he has a tumor or fracture in his spine that could be compressing his spinal cord?

All of the Fruits and veggies work well! I have the leg weakness also. It was discovered that I had 2 small tumors on middle spine and lower spine . Remove with radiation! still have some minor pain sometimes, I have found that 3 Aleve tabs kills the little pain and...........................I take a long NAP!😁🖖🏼

Dexamethasone is very muscle wasting, leaving you very weak. The other MM Meds are just as bad.

Last March I needed a walker and a wheelchair. By last June I stopped All MM Meds. My PT was minimal help - just getting by with a cane. As of last mid July I went to Planet Fitness Gym (free to senior with Silver Sneakers or similar), 7 days a week for 3 months Non Stop. I rebuilt my legs and arms - I worked my ass-off. Not easy but it can be done. I’m now spending time at an indoor golf range, hitting my 3 wood 200 yards - at 69, that’s pretty good.

It would have been easy to settle with getting around with a cane. I fought back and won my life back.

Good luck with your battle.

All the Best

I also have leg weakness. I was hospitalized and the doctor said Velcade was the issue. I was doing RVD but after cycle 3 things got bad I was falling while walking and getting very dizzy, sometimes after standing and sometimes while moving. I also had stage 4 neuropathy and that wasn’t helping. I’ve been off meds for 2 years and I am still not at 100%. The neurologist said I might be as good as I will ever be but the physical therapist says I will get more strength back. I do PT twice a week and walk when I can. I really recommend a good physical therapist I have improved by seeing one. I must walk with walking poles and I also recommend a pair of those. It’s very hard to stand without assistance but using a higher chair is beneficial. My husband made a 4” high box for my favorite chair to sit on and I can now stand up without his help. Hopefully this helps you. If you have other questions about this please ask I will give you my experience.

During my induction - 12 weeks, I was on Darzalex Faspro weekly, Dex-20 mg weekly, Velcade twice a week and Revlimid 25mg - 14 days On / 7 day off. I became very weak in my legs. A side effect of Dex is it is muscle wasting. My arms and legs became hollowed out with no strength in either. There was a point were I could not lift a 4 pound weight.

I transitioned directly to maintenance and went to Revlimid at 10mg and stopped the Vecade and Dex. I was at Darz at every two weeks and I'll be at Darz monthly at the end of this month. A lot of strength has returned on its own. I can now go from a sitting position to standing with only my legs. I can lift a 24 pound package of bottled water (we're on well water so we buy bottled water).

The Velcade and the Dex were the biggest issues and reducing the Rev helped as well. I had been walking a mile on my tread mill but I've had a head cold for almost three weeks. The antibiotics and other meds to help it made me tired. Hope to get back to walking the daily mile (24 minutes - 2.5 pace) this week, though I do a lot of chores around the house and go grocery shopping (its a bit of walking with the cart as my cane). I still use a cane just for stability.

I continue to have plenty of neuropathy issues from the Dex and Velcade. They are lessor now but still a problem. My Dr just started me on Methylprednisolone to see if it can help me as an alternate to Dex.

I'm 68 - I understand how important it is to have your strength and basic independence - I'm driving again. During induction, that was not possible. It took about two months after induction that I felt strong and alert enough to drive.

Good luck regaining your strength - its really important. Find a good Physical Therapist center. If you're on Medicare, it should be completely covered.