I am on darzalex, dexamethasone, and now they want me to start Parmalyst which is a chemo. I also take a shot of xgeva each month. My light chains keep going up, that is the ratio. I took velcade back in 2015-2016 and now my feet hurt at times and is numb all the time. I just take whatever they want me to take. I hope this nee medicine don’t make me sick. Nothing they have given me the last five to six years has made me sick. God has been good to me. I have been blessed. I don’t think this will help you. We all have to take a combination of medicine and I know each of us hopes and prays that they work for the good on our mm.

I have been on all four for 2 weeks. I take Revlimid 10 mg daily for 14 days then off 14. I started the darzalex once a week 6 weeks ago. I looked schistocytes up and they are connected to TMA and thrombocytopenia.

Hi Bonnie2,
This is a new condition I have not heard of before but I am researching it. If I may ask, how long have you been on all four medications? The length of time could be a factor in the fragmented red cells, possibly. I am dealing with a type of anemia at this time which comes from low B12, which I never knew either. With each day, week, month, and new test results we need to research all medical terminology to understand what they mean. Ask questions of your doctor and people on this sight, we’re all learning new things about this disease together and we’re all here to find answers and support each other. God Bless you and watch over us all.