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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Can Your Type Of Myeloma Change During Treatment?

Can Your Type Of Myeloma Change During Treatment?

Has anyone heard of or had their type of Myeloma change during treatment? I was diagnoised with Kappa Light Chain Myeloma last August 2020. I have been on maintenance with. Revlimid 10 mg and Dara Fas Pro for the last month. My light chain numbers are all in normal range but now I have a Gamma M spike of .14 which is strange. I'm wondering if it could be the Dara that is causing this. I have never had an M Spike before as light chain Myeloma does not produce an M spike.

posted over 1 year ago
A MyMyelomaTeam Member said:

Wendym, Yes it can, Treatments can change Your Myeloma Type. Your chromosomal abnormalities can also change. Cells are constantly replicating and changing. Love, Marcia 🌼🌸🌻

edited, originally posted over 1 year ago
A MyMyelomaTeam Member said:

M-spike is how much protein is in your blood. You are not supposed to have protein in your blood.

posted over 1 year ago
A MyMyelomaTeam Member said:

I would certainly ask your doctor what those readings mean and what their significance is. I wondered about my M-spike, which nosedived after 2 months of chemo but was still not zero. My oncologist said that they would watch for patterns. Luckily, mine has remained low.

posted over 1 year ago
A MyMyelomaTeam Member said:

I have also heard of that happening...Even the MM specialist mentioned it before...

posted over 1 year ago
A MyMyelomaTeam Member said:

Wendym, Not sure its the same as yours, however I was diagnosed as IgA kappa and this past February my IgA Kappa is ok but I have a .20 IgG ? Asked both transplant dr and my oncologists and they said it was a clone? I'm still not comfortable about it but my numbers are stable for now. Still on maintenance Revlimid 10mgs 21/7. Maybe its our bodies going through healing changes? Just keeping a close eye.

posted over 1 year ago
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