Has anyone heard of or had their type of Myeloma change during treatment? I was diagnoised with Kappa Light Chain Myeloma last August 2020. I have been on maintenance with. Revlimid 10 mg and Dara Fas Pro for the last month. My light chain numbers are all in normal range but now I have a Gamma M spike of .14 which is strange. I'm wondering if it could be the Dara that is causing this. I have never had an M Spike before as light chain Myeloma does not produce an M spike.
Wendym, Yes it can, Treatments can change Your Myeloma Type. Your chromosomal abnormalities can also change. Cells are constantly replicating and changing. Love, Marcia 🌼🌸🌻
M-spike is how much protein is in your blood. You are not supposed to have protein in your blood.
I would certainly ask your doctor what those readings mean and what their significance is. I wondered about my M-spike, which nosedived after 2 months of chemo but was still not zero. My oncologist said that they would watch for patterns. Luckily, mine has remained low.
I have also heard of that happening...Even the MM specialist mentioned it before...
Wendym, Not sure its the same as yours, however I was diagnosed as IgA kappa and this past February my IgA Kappa is ok but I have a .20 IgG ? Asked both transplant dr and my oncologists and they said it was a clone? I'm still not comfortable about it but my numbers are stable for now. Still on maintenance Revlimid 10mgs 21/7. Maybe its our bodies going through healing changes? Just keeping a close eye.