You don't "have" to do anything. However, there are certain protocols that have been known to have excellent results. We are all different. Your medical team will suggest a treatment that they think us good for you based on many, many factors. If your disease does not respond well to it or if your body has difficulties handling it, they will try something different. I responded very well to RVD (Revlimid, Velcade and Dextamethazone), others have responded better to different treatments. When one treatment protocol becomes less effective, based on many, many peculiarities to you and your body, your team will try something different. I think you need to have faith in your team and communicate with them. YOU are the mist important member of that Team. Nobody on here knows what is best for you. We only share our own experiences and knowledge in hopes that we will help others while staying informed ourselves. Fantastic new treatments are being discovered all the time that give us all hope.

I am on Revlimid and am told for the rest of my life unless it quits working. See if you can qualify for Celgene to give you your Revlimid for like $25.00 for a prescription. They ask 3 questions 1. Are you a U.S citizen?
Do you make over 100,000 a year?
3. Would you share your medicine. (I think that was it)
They didn't ask for any proof to any of the questions. So my meds went from a projected $750 to $25.00. So no harm in asking. Also call every Cancer foundation because there is money out there to be given away. So call them all.

After a stem cell transplant most doctors will put you on a maintenance program that includes some type of chemo. My oncologist did not place me on Revlimid because I had a secondary cancer. I’m on Velcade every 15 days.

I did a SCT in August and my maintenance drug is Venclexta 800mg daily

I am on Revlimid, Velcade and Dex. They said I would have to take meds for 3 yrs but would they probably change every year.